Citation: Jian Hua YU, Yu Lai HU, Wen Fei TAN, Shi Yan YANG, Yuan Qi YIN. Synthesis and Structure of 1,2-O-(1-Aryl-1-Propylidene)-D-Mannitol[J]. Chinese Chemical Letters, ;1997, 8(12): 1033-1036. shu

Synthesis and Structure of 1,2-O-(1-Aryl-1-Propylidene)-D-Mannitol

State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000

Received Date: 23 June 1997

Fund Project: This project is supported by Union Laboratory of Asymmetric Synthesis (Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences,Hong Kong Polytechnic.and Kuo Ching Chemical Co. Ltd.).

A method for selective reaction of 1-aryl-propane-1-ones with 1,2-dihydroxy group of D-mannitol in the presence of ZnCl₂-BF₃.Et₂O to 1,2-O-(1-aryl-1-propylidene)-D-mannitol (1-4) is described.The compounds were first reported and determined by IR,MS,¹H-/¹³C-NMR spectra,among them the structure of 1 was further defined by X-ray diffraction.
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