Citation: Zong Jin HAN, Zhen Kai DING, Qi Kai ZHANG. PREPARATION OF N-t-BUTYLOXYCARBONYL-Oα-9-FLUORENYLMETHYL ESTER OF ASPARTIC ACID[J]. Chinese Chemical Letters, ;1995, 6(8): 673-674. shu

PREPARATION OF N-t-BUTYLOXYCARBONYL-Oα-9-FLUORENYLMETHYL ESTER OF ASPARTIC ACID

Beijing Institute of Parmacology and Toxicology, 27 Tai Ping Road, Beijing 100850

Received Date: 16 February 1995

The preparation of the α carboxyl 9-fluorenylmethyl(FM) ester of Boc-aspartic acid is described.This new protected amino acid linked to the polymeric support by β carboxyl group offers a convenient strategy for the synthesis of head-to-tail cyclopeptides while the peptides remained attached to the polymeric support.
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