Citation: Zhong Biao ZHANG, Dillip K. MOHANTY. Vicarious Michael Addition[J]. Chinese Chemical Letters, ;2006, 17(4): 561-564. shu

Vicarious Michael Addition

Department of Chemistry, Central Michigan University, Mt. Pleasant, Michigan 48859, USA

Received Date: 14 September 2005

C-H bond can undergo vicarious Michael addition reaction (VMA) with doubleactivated double bond in the absence of strong base and catalyst under mild conditions.Intramolecular H-bonding, electron-withdrawing inductive effect, and steric hindrance at α-position of nucleophile facilitates C-H addition over N-H addition. By using VMA, high branching multiplicity, novel branching pattern, controllable density and distribution of functional groups can be envisioned for novel dendrimer synthesis.
- Michael addition,
- dendrimers,
- C-H bond activation,
- hydrogen bonds,
- synthesis
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