Citation: Guang Xiong ZHOU, Ruo Yun CHEN, Hong CHEN, De Quan YU. Two New Bis-tetrahydrofuran Ring Annonaceous Acetogenins from the Roots of Uvaria calamistrata[J]. Chinese Chemical Letters, ;2000, 11(6): 543-544. shu

Two New Bis-tetrahydrofuran Ring Annonaceous Acetogenins from the Roots of Uvaria calamistrata

Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050

Received Date: 14 January 2000

Two mild-cytotoxic bistetrahydrofuran (THF) ring annonaceous acetogenins named calamistrins F (1) and G (2) were isolated from the ethanolic extract of the roots of U. calamistrata Hance. Their structures including the relative and absolute configurations were determined by chemical derivation and spectral analysis. Calamistrins F and G were a pair of epimers at C-26 which both had THF ring from C-18 to C-25 and three OH groups at C-5, C-17 and C-26.
- Annonaceae,
- acetogenin,
- Uvaria calamistrata,
- calamistrin F,
- calamistrin G
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