Citation: Jiaxu Wang, Jinxie Zhang, Xiuping Wang, Jingying Wang, Lina Chen, Jiahui Cao, Wei Cao, Siyu Liang, Ping Luan, Ke Zheng, Xiao-Kun Ouyang, Li Gao, Xiaowen Ou, Fan Zhang, Meitong Ou, Lin Mei. CaCO₃-coated hollow mesoporous silica nanoparticles for pH-responsive fungicides release[J]. Chinese Chemical Letters, ;2024, 35(12): 109697. doi: 10.1016/j.cclet.2024.109697 shu

CaCO₃-coated hollow mesoporous silica nanoparticles for pH-responsive fungicides release

Jiaxu Wang ^{a, b, 1} ,
Jinxie Zhang ^{a, 1} ,
Xiuping Wang ^{b, 1} ,
Jingying Wang ^{a, b} ,
Lina Chen ^b ,
Jiahui Cao ^a ,
Wei Cao ^a ,
Siyu Liang ^c ,
Ping Luan ^d ,
Ke Zheng ^e ,
Xiao-Kun Ouyang ^f ,
Li Gao ^g ,
Xiaowen Ou ^a ,
Fan Zhang ^{a, *,} ,
Meitong Ou ^{a, *,} ,
Lin Mei ^{a, *,}

a.
State Key Laboratory of Advanced Medical Materials and Devices, Tianjin Key Laboratory of Biomedical Materials, Key Laboratory of Biomaterials and Nanotechnology for Cancer Immunotherapy, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China
b.
Hebei Key Laboratory of Crop Stress Biology, College of Agronomy and Biotechnology, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China
c.
University of Edinburgh, Old College, South Bridge, Edinburgh EH89YL, Scotland, United Kingdom
d.
School of Basic Medical Sciences, Shenzhen University, Shenzhen 518060, China
e.
School of Materials Science and Engineering, Dongguan University of Technology, Dongguan 523808, China
f.
School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China
g.
The Second Affiliated Hospital of Guilin Medical College, Guilin 541199, China

zhangfan@bme.pumc.edu.cn

oumt@bme.pumc.edu.cn

meilin@bme.pumc.edu.cn

Received Date: 26 December 2023
Revised Date: 23 February 2024
Accepted Date: 25 February 2024
Available Online: 2 March 2024

Figures(4)

The utilization of fungicides in plants is very low, emphasizing the need to improve their utilization rates. In this study, the fungicide dimethachlon (Dim) was encapsulated within hollow mesoporous silica (HMSNs), and a coating was formed on the HMSNs surface through the reaction of Na₂CO₃ and CaCl₂, resulting in a pH-responsive delivery system named D/H@CaCO₃, proven valuable in preventing sclerotinia diseases in romaine lettuce. When disease-infested romaine lettuce was treated with D/H@CaCO₃, it degraded in the acidic microenvironment of Sclerotinia sclerotiorum (S. sclerotiorum), allowing for the pH-responsive release of Dim and effectively killing S. sclerotiorum. Moreover, the degraded CaCO₃ coating releases CO₂, which enhances the photosynthetic pigment contents, such as chlorophyll a, chlorophyll b, and carotenoids, in turn promoting plant growth. D/H@CaCO₃ is biologically safe for plants and is environmentally friendly, as confirmed by assessments involving zebrafish and earthworms. Given their antifungal capabilities, the controlled release of fungicides offers potential for plant protection.
- Nanopesticide,
- pH-responsive,
- Controlled release,
- Mesoporous silica nanoparticles,
- Sclerotinia sclerotiorum,
- Dimethachlon
1. [1]
  Y.H. Gao, Y.A. Xiao, K.K. Mao, et al., Chem. Eng. J. 383 (2020) 123169. doi: 10.1016/j.cej.2019.123169
2. [2]
  R. Bagchi, R.E. Gallery, S. Gripenberg, et al., Nature 506 (2014) 85–88. doi: 10.1038/nature12911
3. [3]
  W.J. Zhang, C.H. Hong, R.Y. Wang, et al. Int. J. Biol. Macromol. 219 (2022) 1112–1121. doi: 10.1016/j.ijbiomac.2022.08.168
4. [4]
  C.L. Xu, L.D. Cao, C. Cao, et al., Chem. Eng. J. 452 (2023) 139195. doi: 10.1016/j.cej.2022.139195
5. [5]
  A. Shelar, S.H. Nile, A.V. Singh, et al., Nano Micro Lett. 15 (2023) 153–189. doi: 10.1007/s40820-023-01099-1
6. [6]
  K. Wang, Y. Wang, Y.Y. Wu, et al., Chem. Eng. J. 474 (2023) 146012. doi: 10.1016/j.cej.2023.146012
7. [7]
  M.M. Hossain, F. Sultana, W.Q. Li, L.S.P. Tran, M.G. Mostofa, Cells 12 (2023) 1063. doi: 10.3390/cells12071063
8. [8]
  Z.A. Xie, W.L. Liang, Q.Y. Xiong, et al., Carbohydr. Polym. 291 (2022) 119576. doi: 10.1016/j.carbpol.2022.119576
9. [9]
  W. Wei, L.S. Xu, H. Peng, et al., Nat. Commun. 13 (2022) 2213. doi: 10.1038/s41467-022-29788-2
10. [10]
  C. Zhang, X.M. Wu, Y.Y. Wu, et al., J. Hazard. Mater. 403 (2021) 123888. doi: 10.1016/j.jhazmat.2020.123888
11. [11]
  L.H. Zheng, J.P. Wu, H. Hu, et al., J. Control. Release 361 (2023) 427–442. doi: 10.1016/j.jconrel.2023.07.037
12. [12]
  M. Dong, R. Tang, J. Li, et al., Chin. Chem. Lett. 35 (2024) 108539. doi: 10.1016/j.cclet.2023.108539
13. [13]
  J. Wang, H. Pan, J.Y. Li, et al., Chin. Chem. Lett. 34 (2023) 107828. doi: 10.1016/j.cclet.2022.107828
14. [14]
  C. Xu, H.E. Dobson, M.J. Yu, et al., J. Control. Release 357 (2023) 84–93. doi: 10.1016/j.jconrel.2023.03.036
15. [15]
  L.J. Ju, Z.X. Huang, Q. Shen, et al., Chin. Chem. Lett. 35 (2024) 109450. doi: 10.1016/j.cclet.2023.109450
16. [16]
  R. Tan, X.Y. Qiu, W.Y. Mu, et al., Chin. Chem. Lett. 35 (2024) 108343. doi: 10.1016/j.cclet.2023.108343
17. [17]
  W.C. Li, H.J. Zhou, X.Y. Zhang, et al., ACS Nano 17 (2023) 15199–15215. doi: 10.1021/acsnano.3c05120
18. [18]
  Y. Ding, Z.G. Xiao, F.R. Chen, et al., Sci. Total Environ. 863 (2023) 160900. doi: 10.1016/j.scitotenv.2022.160900
19. [19]
  Z.Q. Shi, Q.Q. Li, L. Mei, Chin. Chem. Lett. 31 (2020) 1345–1356. doi: 10.1016/j.cclet.2020.03.001
20. [20]
  Y.H. Gao, Y.H. Zhang, S. He, et al., Chem. Eng. J. 364 (2019) 361–369. doi: 10.1016/j.cej.2019.01.105
21. [21]
  C.L. Xu, Y.P. Shan, M. Bilal, et al., Chem. Eng. J. 395 (2020) 125093. doi: 10.1016/j.cej.2020.125093
22. [22]
  Y.H. Gao, Y. Liang, H.Q. Dong, et al., ACS Sustain. Chem. Eng. 8 (2020) 5716–5723. doi: 10.1021/acssuschemeng.0c00649
23. [23]
  P. Huang, D.Z. Lian, H.L. Ma, et al., Chin. Chem. Lett. 32 (2021) 3696–3704. doi: 10.1016/j.cclet.2021.06.034
24. [24]
  X.D. Yang, S.M. Ying, S. Zhang, et al., Chin. Chem. Lett. 35 (2024) 108674. doi: 10.1016/j.cclet.2023.108674
25. [25]
  S.J. Song, Y.L. Wang, J. Xie, et al., ACS Appl. Mater. Interfaces 11 (2019) 34258–34267. doi: 10.1021/acsami.9b12564
26. [26]
  L. Boufeldja, F. Boudard, K. Portet, et al., Int. J. Mol. Sci. 24 (2023) 12815. doi: 10.3390/ijms241612815
27. [27]
  L. Loladze, J.M. Nolan, L.H. Ziska, A.R. Knobbe, Mol. Nutr. Food Res. 63 (2019) 1801047. doi: 10.1002/mnfr.201801047
28. [28]
  J.Y. Tang, G. Tang, J.F. Niu, et al., J. Agric. Food Chem. 69 (2021) 2382–2391. doi: 10.1021/acs.jafc.0c06487
29. [29]
  Y.X. Gao, X. Zhang, X.N. Song, et al., Pest Manage. Sci. 80 (2024) 1981–1990. doi: 10.1002/ps.7930
30. [30]
  Q.Q. Li, Z.Q. Shi, M.T. Ou, et al., J. Control. Release 352 (2022) 450–458. doi: 10.1016/j.jconrel.2022.10.042
31. [31]
  R. Mohammadpour, D.L. Cheney, J.W. Grunberger, et al., J. Control. Release 324 (2020) 471–481. doi: 10.1016/j.jconrel.2020.05.027
32. [32]
  Y.X. Wang, L. Zhao, Y.B. Dai, et al., Adv. Mater. 35 (2023) 2307900. doi: 10.1002/adma.202307900
33. [33]
  Y.D. Deng, X.D. Zhang, X.S. Yang, et al., J. Hazard. Mater. 409 (2021) 124502. doi: 10.1016/j.jhazmat.2020.124502
1. [1]
  Jianye Kang , Xinyu Yang , Xuhao Yang , Jiahui Sun , Yuhang Liu , Shutao Wang , Wenlong Song . Carbon dots-enhanced pH-responsive lubricating hydrogel based on reversible dynamic covalent bondings. Chinese Chemical Letters, 2024, 35(5): 109297-. doi: 10.1016/j.cclet.2023.109297
2. [2]
  Yan Liu , Yang Wang , Jiayi Zhu , Xuxian Su , Xudong Lin , Liang Xu , Xiwen Xing . Employing pH-responsive RNA triplex to control CRISPR/Cas9-mediated gene manipulation in mammalian cells. Chinese Chemical Letters, 2024, 35(9): 109427-. doi: 10.1016/j.cclet.2023.109427
3. [3]
  Jiayin Zhou , Depeng Liu , Longqiang Li , Min Qi , Guangqiang Yin , Tao Chen . Responsive organic room-temperature phosphorescence materials for spatial-time-resolved anti-counterfeiting. Chinese Chemical Letters, 2024, 35(11): 109929-. doi: 10.1016/j.cclet.2024.109929
4. [4]
  Yunjie Dang , Yanru Feng , Xiao Chen , Chaoxing He , Shujie Wei , Dingyang Liu , Jinlong Qi , Huaxing Zhang , Shaokun Yang , Zhiyun Niu , Bai Xiang . Development of a multi-level pH-responsive lipid nanoplatform for efficient co-delivery of siRNA and small-molecule drugs in tumor treatment. Chinese Chemical Letters, 2024, 35(12): 109660-. doi: 10.1016/j.cclet.2024.109660
5. [5]
  Qianyun Ye , Yuanyuan Liang , Yuhe Yuan , Xiaohuan Sun , Liqi Zhu , Xuan Wu , Jie Han , Rong Guo . pH-responsive chiral supramolecular cysteine-Zn²⁺-indocyanine green assemblies for triple-level chirality-specific anti-tumor efficacy. Chinese Chemical Letters, 2025, 36(5): 110432-. doi: 10.1016/j.cclet.2024.110432
6. [6]
  Liang-Yu Chang , Li-Ju Xu , Dong Qiu . Shellac-based capsule for long-term controlled releasing urea with a broad soil pH tolerance. Chinese Chemical Letters, 2025, 36(5): 110034-. doi: 10.1016/j.cclet.2024.110034
7. [7]
  Feng Cui , Fangman Chen , Xiaochun Xie , Chenyang Guo , Kai Xiao , Ziping Wu , Yinglu Chen , Junna Lu , Feixia Ruan , Chuanxu Cheng , Chao Yang , Dan Shao . Scalable production of mesoporous titanium nanoparticles through sequential flash nanocomplexation. Chinese Chemical Letters, 2024, 35(4): 108681-. doi: 10.1016/j.cclet.2023.108681
8. [8]
  Zhaomin Tang , Qian He , Jianren Zhou , Shuang Yan , Li Jiang , Yudong Wang , Chenxing Yao , Huangzhao Wei , Keda Yang , Jiajia Wang . Active-transporting of charge-reversal Cu(Ⅱ)-doped mesoporous silica nanoagents for antitumor chemo/chemodynamic therapy. Chinese Chemical Letters, 2024, 35(7): 109742-. doi: 10.1016/j.cclet.2024.109742
9. [9]
  Jichun Li , Zhengren Wang , Yu Deng , Hongxiu Yu , Yonghui Deng , Xiaowei Cheng , Kaiping Yuan . Construction of mesoporous silica-implanted tungsten oxides for selective acetone gas sensing. Chinese Chemical Letters, 2024, 35(11): 110111-. doi: 10.1016/j.cclet.2024.110111
10. [10]
  Di ZHANG , Tianxiang XIE , Xu HE , Wanyu WEI , Qi FAN , Jie QIAO , Gang JIN , Ningbo LI . Construction and antitumor activity of pH/GSH dual-responsive magnetic nanodrug. Chinese Journal of Inorganic Chemistry, 2025, 41(4): 786-796. doi: 10.11862/CJIC.20240329
11. [11]
  Yuqing Liu , Shiling Zhang , Kai Jiang , Shiyue Ding , Limei Xu , Yingqi Liu , Ting Wang , Fenfen Zheng , Weiwei Xiong , Jun-Jie Zhu . Near-infrared light responsive upconversion-DNA nanocapsules for remote-controlled CRISPR-Cas9 genome editing. Chinese Chemical Letters, 2025, 36(5): 110282-. doi: 10.1016/j.cclet.2024.110282
12. [12]
  Rui Wang , He Qi , Haijiao Zheng , Qiong Jia . Light/pH dual-responsive magnetic metal-organic frameworks composites for phosphorylated peptide enrichment. Chinese Chemical Letters, 2024, 35(7): 109215-. doi: 10.1016/j.cclet.2023.109215
13. [13]
  Yuwen Zhu , Xiang Deng , Yan Wu , Baode Shen , Lingyu Hang , Yuye Xue , Hailong Yuan . Formation mechanism of herpetrione self-assembled nanoparticles based on pH-driven method. Chinese Chemical Letters, 2025, 36(1): 109733-. doi: 10.1016/j.cclet.2024.109733
14. [14]
  Wantong Zhang , Zixing Xu , Guofei Dai , Zhijian Li , Chunhui Deng . Removal of Microcystin-LR in lake water sample by hydrophilic mesoporous silica composites under high-throughput MALDI-TOF MS detection platform. Chinese Chemical Letters, 2024, 35(5): 109135-. doi: 10.1016/j.cclet.2023.109135
15. [15]
  Yiran Tao , Chunlei Dai , Zhaoxiang Xie , Xinru You , Kaiwen Li , Jun Wu , Hai Huang . Redox responsive polymeric nanoparticles enhance the efficacy of cyclin dependent kinase 7 inhibitor for enhanced treatment of prostate cancer. Chinese Chemical Letters, 2024, 35(8): 109170-. doi: 10.1016/j.cclet.2023.109170
16. [16]
  Shuang Liang , Jianjun Yao , Dan Liu , Mengli Zhou , Yong Cui , Zhaohui Wang . Tumor-responsive covalent organic polymeric nanoparticles enhancing STING activation for cancer immunotherapy. Chinese Chemical Letters, 2025, 36(3): 109856-. doi: 10.1016/j.cclet.2024.109856
17. [17]
  Ke Wang , Jia Wu , Shuyi Zheng , Shibin Yin . NiCo Alloy Nanoparticles Anchored on Mesoporous Mo2N Nanosheets as Efficient Catalysts for 5-Hydroxymethylfurfural Electrooxidation and Hydrogen Generation. Chinese Journal of Structural Chemistry, 2023, 42(10): 100104-100104. doi: 10.1016/j.cjsc.2023.100104
18. [18]
  Wen Zhong , Dan Zheng , Xukun Liao , Yadi Zhou , Yan Jiang , Ting Gao , Ming Li , Chengli Yang . Elaborate construction of pH-sensitive polymyxin B loaded nanoparticles for safe and effective treatment of carbapenem-resistant Klebsiella pneumoniae. Chinese Chemical Letters, 2025, 36(3): 110448-. doi: 10.1016/j.cclet.2024.110448
19. [19]
  Hao Wang , Meng-Qi Pan , Ya-Fei Wang , Chao Chen , Jian Xu , Yuan-Yuan Gao , Chuan-Song Qi , Wei Li , Xian-He Bu . Post-synthetic modifications of MOFs by different bolt ligands for controllable release of cargoes. Chinese Chemical Letters, 2024, 35(10): 109581-. doi: 10.1016/j.cclet.2024.109581
20. [20]
  Zheyi Li , Xiaoyang Liang , Zitong Qiu , Zimeng Liu , Siyu Wang , Yue Zhou , Nan Li . Ion-interferential cell cycle arrest for melanoma treatment based on magnetocaloric bimetallic-ion sustained release hydrogel. Chinese Chemical Letters, 2024, 35(11): 109592-. doi: 10.1016/j.cclet.2024.109592

Get Citation

PDF

XML

Metrics

PDF Downloads(2)
Abstract views(427)
HTML views(11)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

CaCO3-coated hollow mesoporous silica nanoparticles for pH-responsive fungicides release

Metrics

通讯作者: 陈斌, bchen63@163.com

CaCO₃-coated hollow mesoporous silica nanoparticles for pH-responsive fungicides release