Citation: Xiong Haiqing, He Long, Zhang Yun, Wang Jingpei, Song Xiangzhi, Yang Zhaoguang. A ratiometric fluorescent probe for the detection of hypochlorous acid in living cells and zebra fish with along wavelength emission[J]. Chinese Chemical Letters, ;2019, 30(5): 1075-1077. doi: 10.1016/j.cclet.2019.02.008 shu

A ratiometric fluorescent probe for the detection of hypochlorous acid in living cells and zebra fish with along wavelength emission

Xiong Haiqing ^a ,
He Long ^a ,
Zhang Yun ^a ,
Wang Jingpei ^a ,
Song Xiangzhi ^a,b,*, ,
Yang Zhaoguang ^a,b,*,

a.
College of Chemistry & Chemical Engineering, Central South University, Changsha 410083, China
b.
Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, Changsha 410083, China

xzsong@csu.edu.cn

zgyang@csu.edu.cn

Received Date: 14 December 2018
Revised Date: 17 February 2019
Accepted Date: 18 February 2019
Available Online: 19 May 2019

Figures(7)

A ratiometric fluorescence probe, NClO, for the rapid and selective detection of HClO had been designed and synthesized based on a 1, 8-naphthalimide derivative. Probe NClO displayed a red emission (λ_max=615 nm). In the presence of HClO, the solution of probe NClO gave off a strong green fluorescence (λ_{em, max}=520 nm) with a rapid response (within seconds). This probe had been applied to image HClO in living cells and zebra fish.
- Fluorescent probe,
- Hypochlorous acid,
- Ratiometric,
- Organism,
- Large stokes shift
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