Citation: Tong Lang, Mao Zhifeng, Tang Xiangzheng, Zhang Xuejing, Yan Ming. Cycloaddition of hydrazones and 1, 2-diarylalkynes promoted by t-BuOK/DMF: A convenient synthesis of tetraarylpyrazoles[J]. Chinese Chemical Letters, ;2019, 30(2): 395-397. doi: 10.1016/j.cclet.2018.06.018 shu

Cycloaddition of hydrazones and 1, 2-diarylalkynes promoted by t-BuOK/DMF: A convenient synthesis of tetraarylpyrazoles

Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China

zhangxj33@mail.sysu.edu.cn

yanming@mail.sysu.edu.cn

Received Date: 1 April 2018
Revised Date: 29 May 2018
Accepted Date: 11 June 2018
Available Online: 12 February 2018

Figures(4)

A facile synthesis of tetraarylpyrazoles has been developed via t-BuOK/DMF promoted intermolecular cycloaddition of hydrazones and 1, 2-diarylalkynes. A possible reaction pathway via a hydrazone radical is proposed.
- t-BuOK/DMF,
- Tetraarylpyrazole,
- Hydrazone radical,
- Cyclization
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