Citation: Lian Xiaoqi, Shi Dongxu, Ma Jin, Cai Xiaojun, Gu Zhongwei. Peptide dendrimer-crosslinked inorganic-organic hybrid supramolecular hydrogel for efficient anti-biofouling[J]. Chinese Chemical Letters, ;2018, 29(3): 501-504. doi: 10.1016/j.cclet.2017.08.014 shu

Peptide dendrimer-crosslinked inorganic-organic hybrid supramolecular hydrogel for efficient anti-biofouling

Lian Xiaoqi ^a ,
Shi Dongxu ^a ,
Ma Jin ^a ,
Cai Xiaojun ^a,b,, ,
Gu Zhongwei ^a,b,,

a.
National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610065, China
b.
College of Materials Science and Engineering, Nanjing Tech University, Nanjing 211816, China

Corresponding author: Cai Xiaojun, cxj520118@aliyun.com Gu Zhongwei, zwgu@scu.edu.cn
Received Date: 16 June 2017
Revised Date: 31 July 2017
Accepted Date: 13 August 2017
Available Online: 18 March 2017

Figures(6)

We reported a kind of inorganic-organic hybrid supramolecular hydrogel with excellent anti-biofouling capability. The hydrogel was formed via ionic interaction between the negative-charged sodium polyacrylate (SPA) entwined clay nanosheets (CNS) and positive-charged polyhedral oligomeric silsesquioxane (POSS) core-based generation one (L-Arginine) dendrimer (POSS-R). Due to their strong ionic interaction, this kind of hydrogel exhibited a rapid gelation behavior which accomplished even at a low POSS-R concentration about 1% w/v. With the increase of POSS-R concentration, these hydrogels appeared more compact structure, accompanied by remarkable enhanced mechanical strength. In addition, these hydrogels demonstrated rapid thixotropic response and shape-memory capability, as well as good biocompatibility. More importantly, these hydrogels exhibited outstanding anti-biofouling property due to the inherent anti-biofouling capability of SPA. Overall, these findings demonstrated a novel sort of inorganic-organic hybrid supramolecular hydrogel with tunable mechanical strength and excellent anti-biofouling capability, which may have a broad application potential in tissue engineering.
- Peptide dendrimer,
- Supramolecular hydrogel,
- Anti-biofouling
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