Citation: Zhang Yan, Liu Yun-Bao, Li Yong, Ma Shuang-Gang, Li Li, Qu Jing, Zhang Dan, Jiang Jian-Dong, Yu Shi-Shan. Phenolic constituents from the roots of Alangium chinense[J]. Chinese Chemical Letters, ;2017, 28(1): 32-36. doi: 10.1016/j.cclet.2016.05.012 shu

Phenolic constituents from the roots of Alangium chinense

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China

Corresponding author: Yu Shi-Shan, yushishan@imm.ac.cn
Received Date: 11 April 2016
Revised Date: 3 May 2016
Accepted Date: 10 May 2016
Available Online: 24 January 2016

Figures(2)

Three new phenolics (1-3) and twenty-eight known compounds (4-31) were isolated from an ethanolic extract of roots of Alangium chinense. Compound 11 exhibited antiviral activity against Coxsackie virus B3 with IC₅₀ values of 16.89 μmol/L. Compounds 1, 10-17, 19-21, and 23 showed strong antioxidant activity against Fe²⁺-cysteine-induced rat liver microsomal lipid peroxidation, with IC₅₀ values of 0.14-8.18 μmol/L.
- Phenolics,
- Alangium chinense,
- Antiviral,
- Coxsackie virus B3,
- Antioxidant
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