Citation: Wei-Xia Song, Qing-Lan Guo, Yong-Chun Yang, Jian-Gong Shi. Two homosecoiridoids from the fl ower buds of Lonicera japonica[J]. Chinese Chemical Letters, ;2015, 26(5): 517-521. doi: 10.1016/j.cclet.2014.11.035 shu

Two homosecoiridoids from the fl ower buds of Lonicera japonica

1.
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China

Corresponding author: Jian-Gong Shi,
Received Date: 29 January 2014
Available Online: 21 November 2014
Fund Project:

Two new homosecoiridoids, named loniaceticiridoside (1) and lonimalondialiridoside (2), were isolated from an aqueous extract of the flower buds of Lonicera japonica. Their structures including the absolute configuration were determined by extensive spectroscopic studies, especially by 2D NMR and CD data analysis. A proposed biosynthetic pathway and preliminary investigations of the biological activity of compounds 1 and 2 are also discussed.
- Lonicera japonica,
- Homosecoiridoids,
- Loniaceticiridoside,
- Lonimalondialiridoside,
- Anti-inflammatory activity
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