Citation: Hong-Qiang Liu, Jun Liu, Yang-Hui Zhang, Chang-Dong Shao, Jing-Xun Yu. Copper-catalyzed amide bond formation from formamides and carboxylic acids[J]. Chinese Chemical Letters, ;2015, 26(1): 11-14. doi: 10.1016/j.cclet.2014.09.007 shu

Copper-catalyzed amide bond formation from formamides and carboxylic acids

1.
a Department of Chemistry, Tongji University, Shanghai 200092, China;
2.
b Key Laboratory of Yangtze River Water Environment, Ministry of Education, Tongji University, Shanghai 200092, China

Corresponding author: Yang-Hui Zhang,
Received Date: 15 May 2014
Available Online: 14 July 2014
Fund Project: The work was supported by the National Natural Science Foundation of China (No. 21372176) (No. 21372176) and the Program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning. (No. 11 J1409800)

A highly efficient copper-catalyzed approach to form amide bonds from formamides and carboxylic acids was developed. This protocol shows broad substrate scopes and high yields in the presence of 1 mol% catalyst and 4.0 equiv. formamides.
- Amides,
- Formamides,
- Carboxylic acids,
- Copper,
- Catalysis
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沈阳化工大学材料科学与工程学院沈阳 110142