Citation: Kaushal K. Oza, Paresh N. Patel, Hasmukh S. Patel. Synthesis of some novel divalent transition metal complexes as antimicrobials[J]. Chinese Chemical Letters, ;2011, 22(8): 935-938. doi: 10.1016/j.cclet.2011.01.025 shu

Synthesis of some novel divalent transition metal complexes as antimicrobials

Department of Chemistry, Sardar Patel University, Vallabh Vidyanagar 388120, Gujarat, India

Received Date: 15 November 2010

A novel series of transition metal complexes have been synthesized from the reaction of 5-((3-(methylthio)-5-(pyridin-4-yl)-4H-1,2,4-triazol-4-ylamino)methyl)quinolin-8-ol with transition metal salts. The structures of these compounds have been elucidated by elemental and spectral analysis. Furthermore, compounds were screened for in vitro antimicrobial activity against the representative panel of two Gram-positive and two Gram-negative bacteria and two strains of fungus. The various compounds show potent inhibitory action against test organisms.
- 4-Amino-5-mercapto-1,2,4-lriazoles,
- 8-Hydroxyquinoline,
- Spectroscopic studies,
- Antimicrobial activity
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