Citation:
Zahed Karimi-Jaberi, Hassan Zare, Mohammad Amiri, Naghmeh Sadeghi. Cobalt (Ⅱ) chloride accelerated one-pot three-component synthesis of α-aminophosphonates at room temperature[J]. Chinese Chemical Letters,
;2011, 22(5): 559-562.
doi:
10.1016/j.cclet.2010.11.034
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A simple, efficient, and general method has been developed for the one-pot, three-component synthesis of α-aminophosphonates from condensation reaction of trimethyl phosphite, aryl aldehydes and aryl amines in the presence of CoCl2·6H2O under solvent-free conditions.Thus α-aminophosphonates were synthesized relatively quickly in good yields at room temperature.
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