Citation: Meng Lin Ma, Chuan Hong Ren, Ya Jing Lv, Hua Chen, Xian Jun Li. Synthesis and application of chiral N,N'-dialkylated cyclohexanediamine for asymmetric hydrogenation of aryl ketones[J]. Chinese Chemical Letters, ;2011, 22(2): 155-158. doi: 10.1016/j.cclet.2010.09.025 shu

Synthesis and application of chiral N,N'-dialkylated cyclohexanediamine for asymmetric hydrogenation of aryl ketones

a Department of Chemistry, Xihua University, Chengdu 610039, China;
b Key Lab of Green Chemistry and Technology, Ministry of Education, The Institute of Homogeneous Catalysis, Faculty of Chemistry, Sichuan University, Chengdu 610064, China

Received Date: 12 May 2010

Fund Project: We thank the NSFC (No. 20272037), the NSF of Sichuan (No. 07ZA109), the foundation of Xihua University (No. R0723315) and (No. XZD0912-09) for the financial support of this work.

Chiral N,N'-dialkylated cyclohexanediamine derived ligands have been synthesized and used in the asymmetric hydrogenation of aryl ketones. Optically active alcohols with up to 90% enantiomeric excess were obtained in high yields.
- Chiral diamine,
- Aryl ketone,
- Asymmetric hydrogenation,
- Ruthenium complex
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