Citation: Babak Mokhtari, Roya Azadi, Samira Rahmani-Nezhad. Application of N-thiocyanatosuccinimide as a reagent for the facile conversion of epoxides into thiocyanohydrines[J]. Chinese Chemical Letters, ;2011, 22(1): 21-24. doi: 10.1016/j.cclet.2010.09.004 shu

Application of N-thiocyanatosuccinimide as a reagent for the facile conversion of epoxides into thiocyanohydrines

Department of Chemistry, College of Science, Shahid Chamran University, Ahvaz 61357-43337, Iran

Received Date: 19 April 2010

Fund Project: We thank Shahid Chamran University of Ahvaz for financial support of this investigation.

The use of in situ generated N-thiocyanatosuccinimide with NH₄SCN offers an efficient reagent system for the conversion of epoxides into their corresponding thiocyanohydrines in good to high yields. The major advantages of this method are as follows:use of cheap reagent, high regioselectivity, simple availability of reagent, ease of workup of the reaction.
- N-Thiocyanatosuccinimide,
- Ring opening,
- Epoxide,
- Thiocyanohydrin
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