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Citation: Li Yan Sun, Zhen Liang Liu, Tao Zhang, Shu Bin Niu, Zun Tian Zhao. Three antibacterial naphthoquinone analogues from cultured mycobiont of lichen Astrothelium sp[J]. Chinese Chemical Letters, ;2010, 21(7): 842-845. doi: 10.1016/j.cclet.2010.03.024 shu

Three antibacterial naphthoquinone analogues from cultured mycobiont of lichen Astrothelium sp

a College of Pharmacology, Taishan Medical University, Taian 271016, China;
b College of Life Sciences, Shandong Normal University, Jinan 250014, China;
c College of Chemistry and Chemical Engineering, Taishan Medical University, Taian 271016, China;
d Key Lab of Systematic Mycology & Lichenology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China

Received Date: 16 November 2009

Fund Project: This project was supported by National Natural Science Foundation of China (no. 302700005) and the Ministry of Science and Technology of the People's Republic of China (MOST, no. 2007Aa021405). We are most grateful to faculty of microbe metabolites structure and function research group and academician of Jiang Chun Wei of Key Lab of Systematic Mycology & Lichenology, Institute of Microbiology, Chinese Academy of Sciences for the use of their laboratories and helping in identification of the compounds. Thanks are also due to the faculty of Analysis Research Center of Institute of Materia Medica, Chinese Academy of Medical Sciences for the measurements of the 1D and 2D spectra, and to Dr. Qing Shui Zeng (Nanjing University) for mass spectra measurements.

A new naphthoquinone compound named 7-hydroxyl-8-methoxyltrypethelone 3 together with two known compounds trypethelone 1 and trypethelone methyl ether 2 was isolated from cultured mycobiunt of Astrothelium sp.The structures were elucidated by 1D and 2D NMR spectroscopic analysis as well as comparison with those reported in literatures.Compound 1 displayed significant antibacterial activity against Bacillus subtilis (ATCC 6633),and showed modest antibacterial activity against Staphylococcus aureus col (MRSA) (CGMCC 1.2465),while compounds 2 and 3 showed modest antibacterial activity against Enterococcus faecalis 850E (CGMCC 1.2135)and S.aureus col (MRSA) (CGMCC 1.2465).
- Astrothelium sp.,
- Lichen,
- Mycobiont,
- 7-Hydroxyl-8-methoxyltrypethelone
1. [1]
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2. [2]
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3. [3]
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4. [4]
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5. [5]
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6. [6]
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7. [7]
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10. [10]
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13. [13]
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15. [15]
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18. [18]
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19. [19]
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