Citation: Wei Fu, Yong Fang Lei, Ya Ling Cai, Dao Nian Zhou, Jin Lan Ruan. A new alkylene dihydrofuran glycoside with antioxidation activity from the root bark of Morus alba L.[J]. Chinese Chemical Letters, ;2010, 21(7): 821-823. doi: 10.1016/j.cclet.2010.02.016 shu

A new alkylene dihydrofuran glycoside with antioxidation activity from the root bark of Morus alba L.

Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation of Hubei Province, College of Pharmacy, Tongji Medical Center, Huazhong University of Science and Technology, Wuhan 430030, China

Received Date: 21 October 2009

Fund Project: The author is grateful to Ping Lang (Department of Analysis, Huazhong University of Science and Technology) for recording NMR spectra.

A new alkylene dihydrofuran glycoside (1) was isolated from the root bark of Morus alba L., along with moracin M-3'-O-β-D-glucopyranoside (2), and moracin M-6,3'-di-O-β-D-glucopyranoside (3). Compound 1 was identified as 2-methylene-3-methoxy-2, 5-dihydrofuran-4-O-β-D-glucopyranoside on the basis of chemical and spectroscopic data including ID and 2D NMR spectral analysis. In addition, the antioxidant activity of 1 was evaluated using the l,l-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azinobis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assay. The IC₅₀ values were 2.49 and 0.45 mg/mL, respectively.
- Morus alba L.,
- Dihydrofuran glycoside,
- Spectral analysis,
- Antioxidation activity
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