Citation: Ming Hui Yang, Le Cai, Mei Hong Li, Xiang Hui Zeng, Ya Bin Yang, Zhong Tao Ding. Three new phenanthrenes from Monomeria barbata Lindl.[J]. Chinese Chemical Letters, ;2010, 21(3): 325-328. doi: 10.1016/j.cclet.2009.11.006 shu

Three new phenanthrenes from Monomeria barbata Lindl.

a Key Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China;
b Department of Biochemistry, Dali College, Dali 671000, China

Received Date: 26 June 2009

Fund Project: This work was supported by a program for New Century Excellent talents in University from MOE (NCET-08-0925), a grant from the Natural Science Foundation of Yunnan Province (No. 2007B021M) and a grant from Yunnan University (No. 2007Q003A).

Three new monophenanthrene compounds were isolated from an acetone extract of the tubers of Monomeria barbata Lindl. (Orchidaceae). Using spectroscopic methods, the structures of compounds 1-3 were determined as 1,4,7-trihydroxy-2-methoxy-9,10-dihydrophenanthrene (1), 1-(p-hydroxybenzoyl)-2-methoxy-4,7-dihydroxy-9,10-dihydrophenunthrene (2), 1,3,8-tri(p-hydroxybenzyl)-4-methoxy-phenanthrene-4,7-diol (3). These compounds showed cytotoxicities on four tumor cell lines (HepG2, HL-60, Skov-3, A431).
- Monomeria barbara,
- Orchidaceae,
- Monophenanthrene,
- Cytotoxicity
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