Citation: Aamer Saeed, Amara Mumtaz. Microwave-accelerated synthesis of some 1-aroyl-3,5-dimethylpyrazoles[J]. Chinese Chemical Letters, ;2008, 19(11): 1305-1308. doi: 10.1016/j.cclet.2008.07.017 shu

Microwave-accelerated synthesis of some 1-aroyl-3,5-dimethylpyrazoles

Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan

Received Date: 21 May 2008

Fund Project: A.M. gratefully acknowledges a research scholarship from HEC Islamabad under HEC Indigenous PhD Scholarship 5000 Scheme.

Rapid and highly efficient synthesis of some 1-aroy1-3,5-dimethylpyrazoles is achieved by the cyclocondensation of corresponding aroyl hydrazides with 2,4-pentanedione in the absence of solvent and catalyst,under microwave irradiation.The reaction proceeds rapidly and is completed within 40-70 s giving a series of 1-aroy1-3,5-dimethylpyrazoles derivatives in high yields.All of the compounds have been characterized by FTIR,¹H NMR,and mass spectroscopy.
- 1,3-Dimethylpyrazole,
- 2,4-Pentanedione,
- Hydrazides,
- Microwave-aceeleratcd
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