Citation: Xue Sen Fan, Xia Wang, Xiao Yan Li. An unexpected reaction of cyanothioacetamide:Novel preparation of pyrazolo[3,4-b]-pyridine derivatives under[J]. Chinese Chemical Letters, ;2008, 19(6): 643-646. doi: 10.1016/j.cclet.2008.03.005 shu

An unexpected reaction of cyanothioacetamide:Novel preparation of pyrazolo[3,4-b]-pyridine derivatives under

School of Chemical and Environmental Sciences, Henan Key Laboratory for Environmental Pollution Control, Henan Normal University, Xinxiang 453007, China

Received Date: 7 November 2007

Fund Project: We are grateful for the financial support from the National Natural Science Foundation of China (No. 20772025).

An unexpected multi-component reaction of cyanothioacetamide with aldehyde and aminopyrazole under MWI was reported. Through this reaction, a series of pyrazolo[3,4-b]-pyridine derivatives was prepared in high yields via simple operational procedure.
- Pyrazolo[3,4-b]-pyridine,
- Microwave irradiation,
- Thioacetamide
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