Citation: Guo Qiang Shangguan, Lun Liang Huang, Xiao Gang Qu. The synthesis and cytotoxic activity of novel organogermanium sesquioxides with anthraquinone or naphthalene moiety[J]. Chinese Chemical Letters, ;2007, 18(11): 1347-1350. doi: 10.1016/j.cclet.2007.09.029 shu

The synthesis and cytotoxic activity of novel organogermanium sesquioxides with anthraquinone or naphthalene moiety

a Department of Pharmacy, Jining Medical College, Rizhao 276826, China;
b Key Laboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China

Received Date: 29 June 2007

Four novel organogermanium sesquioxides with anthraquinone or naphthalene moiety were synthesized. The structures were characterized by IR, NMR and elemental analysis, and their cytotoxicities were evaluated against human chronic myeloid leukemia K562 cell lines. The cytotoxicity could be improved by the introduction of planar aromatic chromophore moiety to the parent compound, Ge-132.
- Organogermanium sesquioxide,
- Synthesis,
- Cytotoxicity
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