Citation: Shi Yong Fan, Chun Lai Mi, Jun Yang, Song Li, Zhi Bing Zheng. Synthesis of a new series of anti-rhinovirus compounds[J]. Chinese Chemical Letters, ;2007, 18(4): 400-402. doi: 10.1016/j.cclet.2007.02.008 shu

Synthesis of a new series of anti-rhinovirus compounds

a Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China;
b School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China

Received Date: 29 November 2006

Fund Project: This work was supported by the National Basic Research Program of China (No. 2004CB 518908) and the National Natural Science Foundation of China (No. 30472092).

The synthesis of a series of 3,6-dichloropyridazine derivatives was described. In vitro experiment, all compounds exhibited an anti-rhinovirus activity, and one of the compounds 6g showed the comparable activity as our lead compound pirodavir.
- 3,6-Dichoropyridazine derivatives,
- Synthesis,
- Anti-rhinovirus
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