Two new 19-oxygenated ent-kaurane diterpenoids from Isodon pharicus

Yong Zhao Jian Xin Pu Sheng Xiong Huang Li Bin Yang Wei Lie Xiao Li Mei Li Li Sheng Ding Han Dong Sun

引用本文: Yong Zhao,  Jian Xin Pu,  Sheng Xiong Huang,  Li Bin Yang,  Wei Lie Xiao,  Li Mei Li,  Li Sheng Ding,  Han Dong Sun. Two new 19-oxygenated ent-kaurane diterpenoids from Isodon pharicus[J]. Chinese Chemical Letters, 2010, 21(1): 81-84. doi: 10.1016/j.cclet.2009.09.009 shu
Citation:  Yong Zhao,  Jian Xin Pu,  Sheng Xiong Huang,  Li Bin Yang,  Wei Lie Xiao,  Li Mei Li,  Li Sheng Ding,  Han Dong Sun. Two new 19-oxygenated ent-kaurane diterpenoids from Isodon pharicus[J]. Chinese Chemical Letters, 2010, 21(1): 81-84. doi: 10.1016/j.cclet.2009.09.009 shu

Two new 19-oxygenated ent-kaurane diterpenoids from Isodon pharicus

  • 基金项目:

    This work was supported financially by the NSFC (No. 30772637 to H.-D. Sun), the NSFC-joint Foundation of Yunnan Province (No. U0832602 to H.-D. Sun), the Major State Basic Research Development Program of China (No. 2009CB522303 and 2009CB940900), the Natural Science Foundation of Yunnan Province (No. 2008CD162), and the Key Project of Knowledge Innovation Project of CAS (No. KSCX2-YW-R-25).

摘要: Two new 19-oxygenated ent-kaurane diterpenoids, pharicinins D and E (1 and 2), together with an artifact, pharicinin D acetal (3) were isolated from the leaves of Isodon pharicus. Their structures were determined by 1D and 2D NMR spectroscopic analysis. All of them were evaluated for their cytotoxicity.

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  • 收稿日期:  2009-06-01
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