引用本文:
Jian Feng Ji, Hui Bin Zhang, Wen Long Huang, Hai Qian, Jin Pei Zhou. A convenient synthesis of ezetimibe analogs as cholesterol absorption inhibitors[J]. Chinese Chemical Letters,
2010, 21(1): 67-69.
doi:
10.1016/j.cclet.2009.08.009
Citation: Jian Feng Ji, Hui Bin Zhang, Wen Long Huang, Hai Qian, Jin Pei Zhou. A convenient synthesis of ezetimibe analogs as cholesterol absorption inhibitors[J]. Chinese Chemical Letters, 2010, 21(1): 67-69. doi: 10.1016/j.cclet.2009.08.009
Citation: Jian Feng Ji, Hui Bin Zhang, Wen Long Huang, Hai Qian, Jin Pei Zhou. A convenient synthesis of ezetimibe analogs as cholesterol absorption inhibitors[J]. Chinese Chemical Letters, 2010, 21(1): 67-69. doi: 10.1016/j.cclet.2009.08.009
A convenient synthesis of ezetimibe analogs as cholesterol absorption inhibitors
摘要:
A convenient method for the synthesis of ezetimibe analogs as cholesterol absorption inhibitors was described. The key step in the synthesis was the intramolecular ring formation through Mitsunobu reaction. Furthermore, a new series of analogs was designed and synthesized.
English
A convenient synthesis of ezetimibe analogs as cholesterol absorption inhibitors
Abstract:
A convenient method for the synthesis of ezetimibe analogs as cholesterol absorption inhibitors was described. The key step in the synthesis was the intramolecular ring formation through Mitsunobu reaction. Furthermore, a new series of analogs was designed and synthesized.
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Key words:
- Ezetimibe
- / Synthesis
- / Cholesterol absorption inhibitor
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