Synthesis of (+) 8-O-Cinnamyl-p-chlorogoniotriol and its Analogues

Hong CHEN Long En ZHOU Yan Jun ZHANG De Quan YU

引用本文: Hong CHEN,  Long En ZHOU,  Yan Jun ZHANG,  De Quan YU. Synthesis of (+) 8-O-Cinnamyl-p-chlorogoniotriol and its Analogues[J]. Chinese Chemical Letters, 1999, 10(6): 449-452. shu
Citation:  Hong CHEN,  Long En ZHOU,  Yan Jun ZHANG,  De Quan YU. Synthesis of (+) 8-O-Cinnamyl-p-chlorogoniotriol and its Analogues[J]. Chinese Chemical Letters, 1999, 10(6): 449-452. shu

Synthesis of (+) 8-O-Cinnamyl-p-chlorogoniotriol and its Analogues

  • 基金项目:

    The work is supported by the National Natural Science Foundation of China and the Doctoral Foundation of State Education Commission of China. We thank the Department of Instrumental Analysis of our Institute for IR. MS. 1HNMR and [α]D28 measurement.

摘要: (+)8-O-Cinnamyl-p-chlorogoniotriol (p-chlorohowiinol A) and its analogues have been synthesised in nine steps from α-D-glucoheptonic-γ-lactonc. Pharmacological tests showed that most of the compounds possessed antitumor activities toward tumor cell in voro.

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  • 收稿日期:  1998-12-30
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