引用本文:
Chang Yan Zhao, Chang Qing Shi, Yuan Wei Chen. Synthesis of urea acetates as potential PPARα/γ dual agonists[J]. Chinese Chemical Letters,
2008, 19(2): 166-168.
doi:
10.1016/j.cclet.2007.12.013
Citation: Chang Yan Zhao, Chang Qing Shi, Yuan Wei Chen. Synthesis of urea acetates as potential PPARα/γ dual agonists[J]. Chinese Chemical Letters, 2008, 19(2): 166-168. doi: 10.1016/j.cclet.2007.12.013

Citation: Chang Yan Zhao, Chang Qing Shi, Yuan Wei Chen. Synthesis of urea acetates as potential PPARα/γ dual agonists[J]. Chinese Chemical Letters, 2008, 19(2): 166-168. doi: 10.1016/j.cclet.2007.12.013

Synthesis of urea acetates as potential PPARα/γ dual agonists
摘要:
In the quest for novel PPARα/γ dual agonists as putative drugs for the treatment of type 2 diabetes and dyslipidemia, we designed and synthesized a series of urea acetates as potential PPARα/γ dual agonists.The structure of the target compounds, intermediates were characterized by 1H NMR, HRMS.
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关键词:
- Oxazole
- / PPAR agonist
- / Type 2 diabetes
- / Urea
- / Ammonolysis
- / Synthesis
English
Synthesis of urea acetates as potential PPARα/γ dual agonists
Abstract:
In the quest for novel PPARα/γ dual agonists as putative drugs for the treatment of type 2 diabetes and dyslipidemia, we designed and synthesized a series of urea acetates as potential PPARα/γ dual agonists.The structure of the target compounds, intermediates were characterized by 1H NMR, HRMS.
-
Key words:
- Oxazole
- / PPAR agonist
- / Type 2 diabetes
- / Urea
- / Ammonolysis
- / Synthesis

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