引用本文:
Wei Ping YIN, Tian Zeng ZHAO, Ling Jie GAO, Da Peng ZOU, Jian Xun KANG. A Novel Sesquiterpene Polyol Ester from Celastrus Angulatus and its Antitumor Activities[J]. Chinese Chemical Letters,
1999, 10(6): 487-490.
Citation: Wei Ping YIN, Tian Zeng ZHAO, Ling Jie GAO, Da Peng ZOU, Jian Xun KANG. A Novel Sesquiterpene Polyol Ester from Celastrus Angulatus and its Antitumor Activities[J]. Chinese Chemical Letters, 1999, 10(6): 487-490.
Citation: Wei Ping YIN, Tian Zeng ZHAO, Ling Jie GAO, Da Peng ZOU, Jian Xun KANG. A Novel Sesquiterpene Polyol Ester from Celastrus Angulatus and its Antitumor Activities[J]. Chinese Chemical Letters, 1999, 10(6): 487-490.
A Novel Sesquiterpene Polyol Ester from Celastrus Angulatus and its Antitumor Activities
摘要:
A new sesquiterpene polyol ester was isolated from the leaves of Celastrus angulatus. Its structure was determined as 1β, 2β,9α-triacetoxy-8α-(α-hydroxyl-isobutyryloxy)-15-benzoyloxy-4α-hydroxy-dihydroagarofuran by means of NMR, MS and IR spectral analysis. Preliminary biological study on antitumor activity revealed that this compound showed strong nonselective cytotoxicity against four of the NCI panel cell lines.
English
A Novel Sesquiterpene Polyol Ester from Celastrus Angulatus and its Antitumor Activities
Abstract:
A new sesquiterpene polyol ester was isolated from the leaves of Celastrus angulatus. Its structure was determined as 1β, 2β,9α-triacetoxy-8α-(α-hydroxyl-isobutyryloxy)-15-benzoyloxy-4α-hydroxy-dihydroagarofuran by means of NMR, MS and IR spectral analysis. Preliminary biological study on antitumor activity revealed that this compound showed strong nonselective cytotoxicity against four of the NCI panel cell lines.
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Key words:
- Celastrus angulatus
- / sesquiterpene polyol ester
- / NMR
- / activities activities
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