Regioselective enzymatic acylation of troxerutin in nonaqueous medium

Yong Mei Xiao Pu Mao Zhen Zhao Liang Ru Yang Xian Fu Lin

引用本文: Yong Mei Xiao,  Pu Mao,  Zhen Zhao,  Liang Ru Yang,  Xian Fu Lin. Regioselective enzymatic acylation of troxerutin in nonaqueous medium[J]. Chinese Chemical Letters, 2010, 21(1): 59-62. doi: 10.1016/j.cclet.2009.08.017 shu
Citation:  Yong Mei Xiao,  Pu Mao,  Zhen Zhao,  Liang Ru Yang,  Xian Fu Lin. Regioselective enzymatic acylation of troxerutin in nonaqueous medium[J]. Chinese Chemical Letters, 2010, 21(1): 59-62. doi: 10.1016/j.cclet.2009.08.017 shu

Regioselective enzymatic acylation of troxerutin in nonaqueous medium

  • 基金项目:

    No. 82102330014), China, for financially supported to this work.

    We thank the Science and Technology hall of Henan Province (No. 072300420070

摘要: A series of monosubstituted troxerutin esters have been synthesized by enzyme-catalyzed regioselective acylation of troxerutin in nonaqueous medium. Using divinyl dicarboxylates (CH2=CH-OOC-(CH2)n-COO-CH=CH2, n=2, 3, 4, 7, 8, 11) featuring different chain length as acyl donors and alkaline protease from Bacillus subtilis as catalyst, troxerutin was regioselective acylated at B' ethoxyl group. The results indicated that the regioselectivity of the enzyme-catalyzed acylation was not affected by the chain length of the acyl donor.

English

  • 加载中
计量
  • PDF下载量:  2
  • 文章访问数:  830
  • HTML全文浏览量:  27
文章相关
  • 收稿日期:  2008-07-08
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

/

返回文章