引用本文:
Yu Li, Hui Bin Zhang, Wen Long Huang, Xia Zhen, Yun Man Li. Synthesis and biological evaluation of tetrahydroisoquinoline derivatives as potential multidrug resistance reversal agents in cancer[J]. Chinese Chemical Letters,
2008, 19(2): 169-171.
doi:
10.1016/j.cclet.2007.12.016
Citation: Yu Li, Hui Bin Zhang, Wen Long Huang, Xia Zhen, Yun Man Li. Synthesis and biological evaluation of tetrahydroisoquinoline derivatives as potential multidrug resistance reversal agents in cancer[J]. Chinese Chemical Letters, 2008, 19(2): 169-171. doi: 10.1016/j.cclet.2007.12.016
Citation: Yu Li, Hui Bin Zhang, Wen Long Huang, Xia Zhen, Yun Man Li. Synthesis and biological evaluation of tetrahydroisoquinoline derivatives as potential multidrug resistance reversal agents in cancer[J]. Chinese Chemical Letters, 2008, 19(2): 169-171. doi: 10.1016/j.cclet.2007.12.016
Synthesis and biological evaluation of tetrahydroisoquinoline derivatives as potential multidrug resistance reversal agents in cancer
摘要:
Tetrahydroisoquinoline derivatives were synthesized and their multidrug resistance reversal activities were evaluated in vitro.The results showed that some of the synthetic compounds had higher multidrug resistance (MDR) reversal activities than verapamil.
English
Synthesis and biological evaluation of tetrahydroisoquinoline derivatives as potential multidrug resistance reversal agents in cancer
Abstract:
Tetrahydroisoquinoline derivatives were synthesized and their multidrug resistance reversal activities were evaluated in vitro.The results showed that some of the synthetic compounds had higher multidrug resistance (MDR) reversal activities than verapamil.
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Key words:
- Tetrahydroisoquinoline derivatives
- / Synthesis
- / Multidrug resistance (MDR)
- / Peptoids
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