引用本文:
Qun Lu, Hao Lun Tang, Yan Qiang Shao, Jun Chao Cai. A new facile synthesis of shikalkin[J]. Chinese Chemical Letters,
2008, 19(2): 172-174.
doi:
10.1016/j.cclet.2007.11.031
Citation: Qun Lu, Hao Lun Tang, Yan Qiang Shao, Jun Chao Cai. A new facile synthesis of shikalkin[J]. Chinese Chemical Letters, 2008, 19(2): 172-174. doi: 10.1016/j.cclet.2007.11.031

Citation: Qun Lu, Hao Lun Tang, Yan Qiang Shao, Jun Chao Cai. A new facile synthesis of shikalkin[J]. Chinese Chemical Letters, 2008, 19(2): 172-174. doi: 10.1016/j.cclet.2007.11.031

A new facile synthesis of shikalkin
摘要:
A short and convergent approach for the synthesis of shikalkin (dl-shikonin) is presented.Stobbe reaction was employed to construct the aromatic skeleton 6.This is followed by a practical method to prepare the key epoxides 9 from aldehydes 8 in high yield.Finally, shikalkin is achieved by CJrignard reaction and oxidation.
English
A new facile synthesis of shikalkin
Abstract:
A short and convergent approach for the synthesis of shikalkin (dl-shikonin) is presented.Stobbe reaction was employed to construct the aromatic skeleton 6.This is followed by a practical method to prepare the key epoxides 9 from aldehydes 8 in high yield.Finally, shikalkin is achieved by CJrignard reaction and oxidation.

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