Molecular Spectroscopic Study on the Interaction between Heparin and Neutral Red

Li ZHANG Na LI Feng Lin ZHAO Ke An LI

引用本文: Li ZHANG,  Na LI,  Feng Lin ZHAO,  Ke An LI. Molecular Spectroscopic Study on the Interaction between Heparin and Neutral Red[J]. Chinese Chemical Letters, 2004, 15(6): 671-674. shu
Citation:  Li ZHANG,  Na LI,  Feng Lin ZHAO,  Ke An LI. Molecular Spectroscopic Study on the Interaction between Heparin and Neutral Red[J]. Chinese Chemical Letters, 2004, 15(6): 671-674. shu

Molecular Spectroscopic Study on the Interaction between Heparin and Neutral Red

摘要: The interaction between heparin and neutral red was investigated by molecular spectroscopic methods. The change of all spectra suggested that positively charged neutral red had interacted with negatively charged heparin. The study of influence factors indicated that electrostatic force and hydrophobic bond might be involved in the interaction. The total binding number per disaccharide unit and intrinsic binding constant were obtained using Scatchard model.

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  • 收稿日期:  2003-05-13
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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