Diastereoselective α-Alkylation of β-Amino Esters:Preparation of Novel α-Substituted β-Amino Esters from α-Amino Acids

Zhi Hua MA Cong LIU Yong Hua ZHAO Wei LI Jian Bo WANG

引用本文: Zhi Hua MA,  Cong LIU,  Yong Hua ZHAO,  Wei LI,  Jian Bo WANG. Diastereoselective α-Alkylation of β-Amino Esters:Preparation of Novel α-Substituted β-Amino Esters from α-Amino Acids[J]. Chinese Chemical Letters, 2002, 13(8): 721-724. shu
Citation:  Zhi Hua MA,  Cong LIU,  Yong Hua ZHAO,  Wei LI,  Jian Bo WANG. Diastereoselective α-Alkylation of β-Amino Esters:Preparation of Novel α-Substituted β-Amino Esters from α-Amino Acids[J]. Chinese Chemical Letters, 2002, 13(8): 721-724. shu

Diastereoselective α-Alkylation of β-Amino Esters:Preparation of Novel α-Substituted β-Amino Esters from α-Amino Acids

  • 基金项目:

    The project is generously supported by the National Natural Science Foundation of China (Grant No.29972002, 20172002), the Trans-Century Training Programme Foundation for the Talents by Ministry of Education, and Bayer Co. Ltd (Germany). We thank Dr. Schcrkcnbcck for the helpful discussion.

摘要: Enantiomerically pure α-substituted β-amino esters were prepared from natural L-α-amino acids through Arndt-Eistert homologation and diastereoselective α-alkylation.

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  • 收稿日期:  2001-11-27
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