引用本文:
Wei Shuo FANG, Ying LIU, Qi Cheng FANG. First Synthesis of 2α-Thiol Ether Analog of Docetaxel[J]. Chinese Chemical Letters,
2002, 13(8): 708-710.
Citation: Wei Shuo FANG, Ying LIU, Qi Cheng FANG. First Synthesis of 2α-Thiol Ether Analog of Docetaxel[J]. Chinese Chemical Letters, 2002, 13(8): 708-710.
Citation: Wei Shuo FANG, Ying LIU, Qi Cheng FANG. First Synthesis of 2α-Thiol Ether Analog of Docetaxel[J]. Chinese Chemical Letters, 2002, 13(8): 708-710.
First Synthesis of 2α-Thiol Ether Analog of Docetaxel
摘要:
A 2α-phenylthio ether analog 1c of docetaxel was synthesized for the first time from 10-deacetylbaccatin Ⅲ 3 via double inversion of C-2 configuration. This compound showed very weak cytotoxicity toward several tumor cell lines.
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关键词:
- Paclitaxel
- / docetaxel
- / thiol ether
English
First Synthesis of 2α-Thiol Ether Analog of Docetaxel
Abstract:
A 2α-phenylthio ether analog 1c of docetaxel was synthesized for the first time from 10-deacetylbaccatin Ⅲ 3 via double inversion of C-2 configuration. This compound showed very weak cytotoxicity toward several tumor cell lines.
-
Key words:
- Paclitaxel
- / docetaxel
- / thiol ether
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