Selective Cyclooxygenase-2 Inhibitors:Design and Synthesis

Xin Sheng LEI Zong Ru GUO Ling Bo QU Qi Qing ZHU

引用本文: Xin Sheng LEI,  Zong Ru GUO,  Ling Bo QU,  Qi Qing ZHU. Selective Cyclooxygenase-2 Inhibitors:Design and Synthesis[J]. Chinese Chemical Letters, 1999, 10(6): 469-472. shu
Citation:  Xin Sheng LEI,  Zong Ru GUO,  Ling Bo QU,  Qi Qing ZHU. Selective Cyclooxygenase-2 Inhibitors:Design and Synthesis[J]. Chinese Chemical Letters, 1999, 10(6): 469-472. shu

Selective Cyclooxygenase-2 Inhibitors:Design and Synthesis

  • 基金项目:

    This project supported by the National Natural Science Foundation of China. No 39770877.

摘要: The discovery of COX-2 provides a novel target developing more ettective NSAIDs with fewer side effects. On the basis of results from the structure-activity relationships (SAR) of selective COX-2 inhibitors. we have designed and synthesized some promising compounds.

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  • 收稿日期:  1999-03-24
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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