Citation: Shi Shan YU, Zhong Mei ZOU, Jie ZEN, De Quan YU, PU Zhu CONG. Four New Steroidal Alkaloids from the Roots of Sarcococca Vagans[J]. Chinese Chemical Letters, ;1997, 8(6): 511-514. shu

Four New Steroidal Alkaloids from the Roots of Sarcococca Vagans

Shi Shan YU ^a,b ,
Zhong Mei ZOU ^a,b ,
Jie ZEN ^a,b ,
De Quan YU ^a,b ,
PU Zhu CONG ^b

a Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union MedicaI College, Beijing 100050;
b Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union MedicaI College, Beijing 100050

Received Date: 20 January 1997

Four new steroidal alkaloids,named sarcovagine A-D,were isolated from the roots of Sarcococca vagans.Their structures were determined as 20α-dimemylamino-2β,4β-dihydroxy-3β-tigloylamino-5α-pregnane (sarcovagine A,1),20α-dimethylamino-2α-hydroxy-4β-acetoxy-3β-tigloylamino-5α-pregnane (sarcovagine B,2),20α-dimethylamino-4β-acetoxy-3β-tigloylamino-5α-pregnane (sarcovagine C,3),20α-dimemylamino-3-tigloylamino-5α-pregn-2(3)-en-4-one (sarcovagine D,4),respectively.
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