Citation: Shao Yi SUN, De Quan YU. Synthesis of 7-Epi-howiinol A[J]. Chinese Chemical Letters, ;1997, 8(10): 863-864. shu

Synthesis of 7-Epi-howiinol A

Shao Yi SUN ,
De Quan YU

Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050

Received Date: 25 June 1997

Fund Project: This work is supported by the National Natural Science Foundation of China and the Doctoral Foundation of the Stale l.Education Commission of China. We thank the Department of instrumental Analysis of our Institute for IR MS NMR measurements.

7-Epi-howiinol A,an antitumor lactone,has been synthesized in nine steps starting from α-D-glucoheptonic γ-lactone with an overall yield of 8.5%.
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