Citation: Tian Ying AN, Li Hong HU, Rong Min CHEN, Zhong Liang CHEN, Jia LI, Qiang SHEN. Anti-diabetes Agents——Ⅰ: Tetralone Derivative from Juglans regia[J]. Chinese Chemical Letters, ;2003, 14(5): 489-490. shu

Anti-diabetes Agents——Ⅰ: Tetralone Derivative from Juglans regia

Chinese National Center for Drug Screening, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031

Received Date: 21 June 2002

Fund Project: This work was supported by the National Natural Science Fundation of China (30100229) and Science and Technology Development Fundation of Shanghai, China (01QB14051), and these supports are gratefully acknowledged.

A new compound, 4-hydroxy-α-tetralone-4-O-β-D-[6'-O-(3",4",5"-trihydroxybenzoyl) glucopyranoside (1), together with a known compound, 4-hydroxy-α-tetralone (2), has been isolated from the roots of Juglans regia.2 showed moderate bioactivity against protein tyrosine phosphatase 1B (PTP1B).
- Juglans regia,
- Juglandaceae,
- tetralone,
- PTP1B inhibitor
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