Citation: Tao CHEN, Tian Bao HUANG. RESOLUTION OF DL-α-AMINO ACIDS ON A L-HYDROXY PROLINE CHIRAL PHASE BY LIGAND-EXCHANGE CHROMATOGRAPHY[J]. Chinese Chemical Letters, ;1995, 6(5): 383-384. shu

RESOLUTION OF DL-α-AMINO ACIDS ON A L-HYDROXY PROLINE CHIRAL PHASE BY LIGAND-EXCHANGE CHROMATOGRAPHY

Tao CHEN ,
Tian Bao HUANG

Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041

Received Date: 29 November 1994

A HPLC bonded phase with L-hydroxy proline was prepared by coupling L-hydroxy proline as a chiral selector to silica gel via 3-glycidyloxypropyltrimethoxysilane.The chiral separations of 12 DL-amino acids on the chiral phase were performed and the effects of the chromatographic conditions,the pH of the mobile phase and the column temperature,on the resolution of DL-α-amino acids were studied.
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