Citation: Guo Hua GAO, Jin Bao GAO, Wen Juan ZHOU, Liang LU, Ming Yuan HE. Aqueous Knoevenagel Condensation Catalyzed by Aminopropyl-functionalized MCM-41[J]. Chinese Chemical Letters, ;2006, 17(10): 1293-1296. shu

Aqueous Knoevenagel Condensation Catalyzed by Aminopropyl-functionalized MCM-41

Shanghai Key Laboratory of Green Chemistry and Chemical Process, Department of Chemistry, East China Normal University, Shanghai 200062

Received Date: 6 April 2006

Fund Project: This work was financially supported by SRF for ROCS, SEM and Science and Technology Commission of Shanghai Municipality under grant No. 05DJ14002.

An efficient, environmentally friendly procedure is developed for the condensation of aldehydes/ketones and activatedmethylene compounds by using an aminopropyl-functionalized MCM-41 catalyst in aqueoussolution. Different aldehydes/ketones and activated methylene compounds gave thecorresponding alkenes in 78-97% isolated yields in mild reaction conditions.In comparison with organic solution, the aqueous solution gives higher yields in the same reaction conditions. Furthermore, the aminopropyl-functionalized MCM-41 in aqueous system can be reused for 8 times without significant decrease of activity.
- Knoevenagel condensation,
- aqueous-phase reaction,
- aminopropyl-functionalized MCM41
1. [1]
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2. [2]
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3. [3]
  Tianwen Chen , Chunqiang Cai , Li Chen , Yanlin Chen , Lichun Dong , Luxi Tan , Zitong Liu . Novel vinylene-bridged covalent organic framework based on diketopyrrolopyrrole with exceptional photothermal properties. Chinese Chemical Letters, 2025, 36(7): 111028-. doi: 10.1016/j.cclet.2025.111028
4. [4]
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5. [5]
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6. [6]
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7. [7]
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8. [8]
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11. [11]
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12. [12]
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13. [13]
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14. [14]
  Yu Pang , Min Wang , Ning-Hua Yang , Min Xue , Yong Yang . One-pot synthesis of a giant twisted double-layer chiral macrocycle via [4 + 8] imine condensation and its X-ray structure. Chinese Chemical Letters, 2024, 35(10): 109575-. doi: 10.1016/j.cclet.2024.109575
15. [15]
  Jingjing Zhang , Lan Ding , Vadim Popkov , Kezhen Qi . Aqueous indium metal batteries. Chinese Chemical Letters, 2025, 36(2): 110407-. doi: 10.1016/j.cclet.2024.110407
16. [16]
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19. [19]
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20. [20]
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