Citation: Xiao-Jiang HAO, Manabu NODE, Kaoru FUJI. Chiral Synthesis of the Intermediate of (-)-Gibberellin A₁₂[J]. Chinese Chemical Letters, ;1997, 8(11): 951-952. shu

Chiral Synthesis of the Intermediate of (-)-Gibberellin A₁₂

a Kunming Institute of Botany, Chinese Academy, of Sciences, Kunming 650204;
b Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607, Japan;
c Institute for Chemical Research, Kyoto University, Uji 611, Japan

Received Date: 4 September 1997

(-)-Dimethyl(1R,4aS)-1,4a-dimethyl-6-nitro-1,2,3,4,4a-pentahydrofluorene-1,9-dicarboxy-late (1) was synthesized from (R)-(+)-2-methyl-2-(2'-nitrovinyl)-δ-valerolactone (2),which constitutes a formal total synthesis of (-)-gibberellin A₁₂.
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