Citation: Jun Gui DAI, Lin YANG, Jun Ichi SAKAI, Masayoshi ANDO. A Taxatetraene from Microbial Transformation of Sinenxan A[J]. Chinese Chemical Letters, ;2005, 16(6): 736-738. shu

A Taxatetraene from Microbial Transformation of Sinenxan A

1.
Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050;
2.
Department of Chemistry and Chemical Engineering, Niigata University, Ikarashi 2-8050, Niigata 950-2181, Japan;
3.
College of Life and Environmental Sciences, The Central University for Nationalities, Beijing 100081

Received Date: 15 June 2004

Fund Project: This work is supported by the National Natural Science Foundation of China (Project No. 30100230) and the Japan Society for the Promotion of Science (Project No. 1300127).

Sinenxan A[2α, 5α, 10β, 14β-tetraacetoxytaxa-4(20), 11-diene, 1] was biotransformed by a filamentous fungus, Aspergillus niger JCM 5546, and an unusual taxatetraene[2α,5α-acetoxytaxa-4(20), 10(11), 12(18), 13(14)-tetraene, 2], together with two known products,10β-deacetyl sinenxan A (3) and 10β, 14β-dideacetyl sinenxan A (4) were produced.
- Aspergillus niger,
- sinenxan A,
- taxatetraene,
- biotransformation
1. [1]
  Hong Zhang , Cui-Ping Li , Li-Li Wang , Zhuo-Da Zhou , Wen-Sen Li , Ling-Yi Kong , Ming-Hua Yang . Asperochones A and B, two antimicrobial aromatic polyketides from the endophytic fungus Aspergillus sp. MMC-2. Chinese Chemical Letters, 2024, 35(9): 109351-. doi: 10.1016/j.cclet.2023.109351
2. [2]
  Aimin Fu , Chunmei Chen , Qin Li , Nanjin Ding , Jiaxin Dong , Yu Chen , Mengsha Wei , Weiguang Sun , Hucheng Zhu , Yonghui Zhang . Niduenes A−F, six functionalized sesterterpenoids with a pentacyclic 5/5/5/5/6 skeleton from endophytic fungus Aspergillus nidulans. Chinese Chemical Letters, 2024, 35(9): 109100-. doi: 10.1016/j.cclet.2023.109100
3. [3]
  Xia Wei , Zheng-Wu Luo , Guo-Qiang Zhang , Yan-An Lin , Ze-Kun Zhang , Lin-Kun An , Xi-Xin He , Jun-Cheng Su , Cui-Xian Zhang . Sterpiperazines A and B, steroid-indole alkaloids with Tdp1 inhibitory and chemotherapy sensitizing activities from marine fungus Aspergillus sp. EGF 15-0-3. Chinese Chemical Letters, 2026, 37(2): 111048-. doi: 10.1016/j.cclet.2025.111048
4. [4]
  Hai-Ying Yu , Yu-Wei Huang , Li-Ping Lin , Ren-Xiang Tan . Unprecedented diphenyl ether hybrids and spiro-diphenyl ether with antioxidant activity from Aspergillus sp. F1-8A associated with toad venom. Chinese Chemical Letters, 2026, 37(2): 111121-. doi: 10.1016/j.cclet.2025.111121

Get Citation

PDF

XML

Metrics

PDF Downloads(1)
Abstract views(1491)
HTML views(32)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Address：Zhongguancun North First Street 2,100190 Beijing, PR China Tel: +86-010-82449177-888

DownLoad: Full-Size Img PowerPoint

Return