Citation: Bi Yun SUN, Ai Jin HUANG, Yi Liang SUN, Zeng Pei SUN. Quantitative Analysis of Anti-hypertensive Compound Formulations by Capillary Zone Electropboresis[J]. Chinese Chemical Letters, ;1997, 8(11): 989-992. shu

Quantitative Analysis of Anti-hypertensive Compound Formulations by Capillary Zone Electropboresis

a Department of Chemistry, Peking University, Beijing 100871;
b National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050

Received Date: 14 July 1997

Fund Project: The financial support of this work provided by the Doctoral Program Foundation of the State Educational Commission of China is gratefully acknowledged.

Two capillary electrophoresis methods were developed for the determination of the active constituents in four anti-hypertensive formulations.These active constituents are nitrendipine and atenolol in Tabellae Nile,and hydrochlorothiazide,amiloride hydrochloride,captopril,and enalapril maleate in three other tablet formulations,respectively The internal standard method was employed for quantitation with RSD between 1.2~4.3%,recoveries ranging from 93.1~101.0%.
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