Citation: Xiang Qun LI, Zhen Wei MIAO, Yu LUO, Cong Xi LI, You Qi TANG. De Novo Design and Synthesis of Four-Helix Bundle Peptides[J]. Chinese Chemical Letters, ;1996, 7(9): 809-811. shu

De Novo Design and Synthesis of Four-Helix Bundle Peptides

Department of Chemistry, Peking University, Beijing 100871

Received Date: 5 March 1996

Fund Project: This work was supported by State Key Projects for Fundamental Research-Important Chemical Problems in Life Process.

Two peptides (LI22 and LI29) designed to form four-helix bundle were synthesized by stepwise solid phase peptide synthesis (SPPS) using Fmoc strategy, purified by reversed phase high performance liquid chromatography (HPLC) and confirmed by fast atom bombardment mass spectrum (FABMS).
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