Citation:
Qin Zheng YANG, Jing YANG, Chang Kai ZHANG. Layered Double Hydroxide as Cordycepin Delivery Nanocarrier[J]. Chinese Chemical Letters,
;2006, 17(7): 985-987.
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Layered double hydroxide was investigated as cordycepin delivery nanocarrier for the first time in this study. Negatively charged biomolecule-cordycepin was intercalated in the gallery spaces of [Mg-Al-NO3], which was confirmed by the results of X-ray diffraction and electrophoretic mobility. Cell experiment suggested that the new bio-LDH nanohybrid could prevent cordycepin decomposition by adenosine deaminase. This new formulation could possibly be used as a novel form cordycepin intravenous injection.
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Keywords:
- Layered double hydroxide,
- cordycepin,
- nanohybrid,
- intercalate
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