Citation: Na WANG, Qi WU, Jian Ming XU, Xiu Ming JIANG, Xian Fu LIN. Regioselective Synthesis of Polymerizable Vinyl Guaifenesin Esters Catalyzed by an Alkaline Protease of Bacillus subtilis[J]. Chinese Chemical Letters, ;2004, 15(2): 175-178. shu

Regioselective Synthesis of Polymerizable Vinyl Guaifenesin Esters Catalyzed by an Alkaline Protease of Bacillus subtilis

Department of Chemistry, Zhejiang University, Hangzhou 310027

Received Date: 2 January 2003

Three polymerizable vinyl guaifenesin esters with different acyl donor carbon chain lengths (C4, C6, C10) were regioselectivly synthesized by an alkaline protease from Bacillus subtilis in pyridine at 50℃ for 1, 3, 5 days respectively.
- Vinyl guaifenesin ester,
- regioselectivity,
- alkaline protease,
- transesterification
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