Citation: Li ZHANG, Na LI, Feng Lin ZHAO, Ke An LI. Molecular Spectroscopic Study on the Interaction between Heparin and Neutral Red[J]. Chinese Chemical Letters, ;2004, 15(6): 671-674. shu

Molecular Spectroscopic Study on the Interaction between Heparin and Neutral Red

Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Department of Chemical Biology, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871

Received Date: 13 May 2003

The interaction between heparin and neutral red was investigated by molecular spectroscopic methods. The change of all spectra suggested that positively charged neutral red had interacted with negatively charged heparin. The study of influence factors indicated that electrostatic force and hydrophobic bond might be involved in the interaction. The total binding number per disaccharide unit and intrinsic binding constant were obtained using Scatchard model.
- Spectroscopic,
- interaction,
- heparin,
- neutral red
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