Citation:
Min ZHU, Xue Mei HUANG, Han Xi SHEN. Activation of Carcinogenic Non-aminoazo Compounds in Horseradish Peroxidase/H2O2 System[J]. Chinese Chemical Letters,
;1997, 8(11): 979-982.
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Eriochrome black T and Nitrosulfophenol S were advocated as the chemical models of carcinogenic non-aminoazo compounds.The main products of their oxidative cleavage in horseradish peroxidase/H2O2 system was identified as the benezenediazonium ion,the ultimate carcinogens,which could bind to DNA.The reaction conditions were investigated preliminarily.Some inhibitors and inducers of the reaction were discovered.
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