Citation: Xiao Ru ZHANG, Ying Xia LI, Shi Dong CHU, Kun Yu YU, Hua Shi GUAN. One-pot Synthesis of Divalent and Trivalent Cluster Mannosides via Ugi Four-component Reaction[J]. Chinese Chemical Letters, ;2003, 14(11): 1130-1132. shu

One-pot Synthesis of Divalent and Trivalent Cluster Mannosides via Ugi Four-component Reaction

Institute of Marine Drugs, Ocean University of China, Qingdao 266003

Received Date: 7 November 2002

The Ugi four-component reaction (U-4CR) was utilized to prepare divalent and trivalent cluster mannosides. Thus, two target compounds 6 and 8 were obtained efficiently using carboxymethyl 2, 3, 4, 6-tetra-O-acetyl-α-D-mannopyranoside 4 as acid component, and 1, 6-hexanediamine or tris(2-aminoethyl)amine as the multivalent scaffolds.
- Ugi reactions,
- cluster mannosides,
- glycocluster
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