Citation: Gui Sheng DENG, Ming Yi LIAO, Xue TIAN, Jian Bo WANG. Regioselective 1,2-Addition of Ti(Ⅳ)-enolate to α, β-Unsaturated Compounds[J]. Chinese Chemical Letters, ;2005, 16(5): 589-592. shu

Regioselective 1,2-Addition of Ti(Ⅳ)-enolate to α, β-Unsaturated Compounds

Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871

Received Date: 27 April 2004

Fund Project: The project is generously supported by NNSFC (Grant No. 20225205, 20172002, 20390050), the Trans-Century Training Programme Foundation for the Talents by the Ministry of Education.

The nucleophilic addition of Ti(Ⅳ) enolate derived from methyl aryl ketones to α, β-unsaturated compounds was found to be highly selective to give 1, 2 addition products.
- Ti(Ⅳ) enolates,
- nucleophilic addition,
- regioselectivity,
- enones,
- Lewis acid
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