Citation: Jin Fa DU, Jin ZHOU, Liang HUANG. PRELIMINARY STUDIES ON THE KINETIC RESOLUTION OF METHYL ERYTHRO-PHENYLGLYCERATE AND METHYL t-EPOXYCINNAMATE BY PLE[J]. Chinese Chemical Letters, ;1992, 3(2): 95-96. shu

PRELIMINARY STUDIES ON THE KINETIC RESOLUTION OF METHYL ERYTHRO-PHENYLGLYCERATE AND METHYL t-EPOXYCINNAMATE BY PLE

Institute of Materia Medica, Chinese Academy of Medical Sciences Beijing, 100050

Received Date: 11 October 1991

Fund Project: The work was supported by the State Education Committee of China for doctorate station.

PLE (pig liver esterase) catalyzed hydrolysis of the title compounds demonstrated that the α-carbon with S configuration hydrolyzed faster than the R configuration and α-carbon controlled the stereoselectivity. The preliminary results showed that the highest ee obtained were only 40-48%.
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